Sporadic Fundic Gland Polyps

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Lysozyme overexpression in fundic gland polyps.

UNLABELLED Backgroud: Helicobacter pylori (Hp) rarely proliferates in patients with fundic gland polyps (FGPs). We recently found that FGPs express lysozyme, one of the natural defence substances against infection. We aimed to assess the degree of lysozyme expression in a cohort of consecutive FGPs. MATERIALS AND METHODS A total of 153 gastric biopsies were investigated: 93 with FGPs, 30 with...

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Fundic gland cysts in Atp4a-/- mice mimic fundic gland polyps in humans.

BACKGROUND Innumerable fundic gland polyps (FGPs) (that is massive FGP polyposis) may be found in the human stomach. Innumerable fundic gland cysts (FGCs) develop in mice lacking the gene Atp4a (Atp4a((-/-))), that encodes the enzyme ATPase. The aim was to monitor the evolution of FGCs in Atp4a((-/-)) mice. MATERIALS AND METHODS Six pairs (male-female) of Atp4a((-/-)) mice, 8, 12 and 20 month...

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Premalignant Potential of Fundic Gland Polyps-associated Familial Polyposis Syndromes

Fundic gland polyps (FGPs) are the most common type of gastric polyps (up to 50%). They are found in up to 0.8-1.9 % of the general population, and in 40-84 % of the patients suffering from familial polyposis syndromes. They might be sporadic or associated to polyposis syndromes. When the former, they should be considered exclusively benign lesions, and possibly related to the chronic use of pr...

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An Unusual Cause of Gastrointestinal Bleeding: Gastric Fundic Gland Polyps

The most usual causes of iron deficiency anemia are related to the digestive disease: acute or chronic blood loss (due to cancer or polyp of colon or stomach, peptic ulcer, nonsteroidal anti-inflammatory drugs use, inflammatory bowel disease, vascular lesions) or reduced iron absorption (in celiac disease, small bowel bacterial overgrowth, Whipple’s disease, lymphangiectasia, gastrectomy and ga...

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Regression of fundic gland polyps following acquisition of Helicobacter pylori.

The prevalence of Helicobacter pylori infection is very low in patients with fundic gland polyps (FGPs) of the stomach. We report here two cases with multiple FGPs that regressed following new H pylori acquisition. Patient Nos I and II had multiple FGPs in normal fundic mucosa without inflammatory changes or atrophy. Both were not infected with H pylori. Following acquisition of H pylori infect...

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ژورنال

عنوان ژورنال: Video Journal and Encyclopedia of GI Endoscopy

سال: 2013

ISSN: 2212-0971

DOI: 10.1016/s2212-0971(13)70084-0